منابع مشابه
The Selegiline Transdermal System (Emsam)
212 P&T® • April 2008 • Vol. 33 No. 4 ABSTRACT Although monoamine oxidase inhib itors (MAOIs) at one time represented the mainstay of therapy for major depressive disorder (MDD), the risk of acute hypertensive reactions following the ingestion of tyramine-rich foods and the consequent need to restrict dietary tyramine represent a barrier to their use. In this article, we present an overview of ...
متن کاملSelegiline transdermal system in major depressive disorder
125 ISSN 1758-2008 10.2217/NPY.12.9 © 2012 Future Medicine Ltd Neuropsychiatry (2012) 2(2), 125–134 Summary Selegiline transdermal system (STS) has been approved to treat major depressive disorder in the USA. STS represents a novel generation of monoamine oxidase inhibitors with a superior safety profile to older monoamine oxidase inhibitors, in particular with regard to food interactions. The ...
متن کاملA critical appraisal of the selegiline transdermal system for major depressive disorder.
The selegiline transdermal system (STS) is the first antidepressant transdermal medication approved by the US FDA for the treatment of major depressive disorder. Its unique antidepressant delivery system allows for steady release of selegiline over 24 h with minimal fluctuation in drug serum levels. It is able to deliver high enough central nervous system concentrations required for an antidepr...
متن کاملTransdermal Iontophoretic Delivery of Selegiline and Prochlorperazine by
........................................................................................................................................ ii Acknowledgments........................................................................................................................ iii List of Tables .........................................................................................................
متن کاملTransdermal selegiline for the treatment of major depressive disorder
Non-selective inhibition of monoamine oxidase (MAO) enzymes (ie, isoforms A and B) in the brain are associated with clinically significant antidepressant effects. In the US, the selegiline transdermal system (STS; EMSAM) is the first antidepressant transdermal delivery system to receive Food and Drug Administration (FDA) approved labeling for the treatment of major depressive disorder (MDD). Cu...
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ژورنال
عنوان ژورنال: The Primary Care Companion For CNS Disorders
سال: 2013
ISSN: 2155-7780
DOI: 10.4088/pcc.12br01466